Research Article
[Retracted] Nucleus Pulposus Cells Induce M2 Polarization of RAW264.7 via CX3CL1/CX3CR1 Pathway and M2 Macrophages Promote Proliferation and Anabolism of Nucleus Pulposus Cells
Figure 7
NPC were spindle in shape and were able to adhering to the wall, while the RAW264.7 macrophages were round in shape, well clustered, and also able to adhering to the wall (a). In the coculture system, RAW264.7 significantly increased the expression of CX3CL1 in NPC (b–d). Besides, NPC significantly induced M2 polarization of RAW264.7 as measured by flow cytometry (e, f) and immunofluorescent staining (g, h). “” indicates . RAW: RAW264.7 macrophages. NPC: nucleus pulposus cells.
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