[Retracted] Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer

Figure 5

Overall survival (OS), disease-free survival (DFS), progression-free survival (PFS), and disease-specific survival (DSS) of individuals with STAD, as affected by PTTG gene mutations (cBioPortal). (a) Here is a rundown of the many forms of cancer associated with PTTG mutations. Gene changes in PTTGs were found in 24.64 percent of 69 instances with tubular STAD. Mutations in green, gene amplifications in red, profound deletions in blue, elevated levels of mRNA in pink, and numerous changes in grey. (b) Research into PTTG gene mutations in GC. Out of 412 STAD patients studied, 16 percent had inherited mutations in their STAT3 gene. Mutation rates for PTTG1, PTTG2, and PTTG3p were 6%, 5%, and 9%, respectively. Punctuation mutations are grey while missense mutations are green. Gene duplications are shown in green and large deletions in blue. (c–f) Survival, progression, and death rates were analyzed using Kaplan-Meier plots separated by the presence or absence of mutations in the PTTG gene.

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