Research Article

[Retracted] Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer

Table 2

Evaluation of the association between PTTG expression and clinical prognosis in gastric cancer using the Kaplan-Meier plotting method and other clinicopathological variables.

Clinicopathological characteristicsPTTG1PTTG2PTTG3P
Overall survival ()
Hazard ratio valueHazard ratio valueHazard ratio value

Sex
 Female2440.44 (0.29-0.65)1.64 (1.16-2.33)0.00490.56 (0.39-0.81)0.0019
 Male5660.79 (0.64-0.98)0.0321.43 (1.15-1.77)0.0010.67 (0.53-0.85)
Stage
 1690.22 (0.05-0.97)0.0283.5 (0.99-12.34)0.0380.34 (0.12-0.92)0.027
 21450.53 (0.28-0.98)0.0391.6 (0.89-2.9)0.120.43 (0.23-0.78)0.0044
 33190.6 (0.45-0.8)0.000511.4 (1.04-1.86)0.0230.68 (0.51-0.9)0.0075
 41520.54 (0.35-0.82)0.00340.75 (0.51-1.11)0.150.64 (0.42-0.98)0.037
Stage T
 22530.61 (0.4-0.93)0.0211.43 (0.86-2.39)0.160.52 (0.34-0.8)0.0022
 32080.69 (0.47-0.99)0.0441.15 (0.82-1.62)0.420.68 (0.49-0.96)0.029
 4390.44 (1.09-1.03)0.0540.7 (0.28-1.79)0.460.63 (0.27-1.49)0.29
Stage N
 0760.25 (0.07-0.84)0.0153.87 (1.65-9.08)0.000830.46 (0.2-1.08)0.068
 12320.5 (0.33-0.75)0.000721.45 (0.96-2.18)0.0760.46 (0.31-0.7)0.00021
 21290.59 (0.37-0.93)0.0210.54 (0.33-0.87)0.111.46 (0.85-2.58)0.16
 3760.49 (0.29-0.85)0.00940.58 (0.32-1.06)0.0710.48 (0.27-0.87)0.013
4370.58 (0.45-0.76)1.14 (0.88-1.48)0.330.55 (0.42-0.73)
Stage M
 04590.55 (0.41-0.73)1.31 (1-1.73)0.0530.53 (0.4-0.7)
 1580.53 (0.29-0.98)0.0390.7 (0.37-1.32)0.260.52 (0.27-1)0.045
Lauren classification
 Intestinal3360.55 (0.4-0.76)0.000241.61 (1.17-2.22)0.00310.5 (0.36-0.68)
 Diffuse2480.63 (0.44-0.9)0.011.33 (0.95-1.88)0.0980.6 (0.4-0.89)0.01
Differentiation
 Poor1661.75 (1.17-2.63)0.00571.28 (0.85-1.92)0.231.2 (0.8-1.81)0.37
 Moderate670.63 (0.31-1.25)0.180.63 (0.33-1.2)0.150.51 (0.26-0.99)0.042
 High320.57 (0.23-1.43)0.231.55 (0.65-3.69)0.320.31 (0.12-0.8)0.011
Treatment
 Surgery alone3930.6 (0.44-0.81)1.2 (0.9-1.6)0.210.61 (0.46-0.82)0.00072
 5 FU-based adjuvant1572.12 (1.4-3.21)0.000321.56 (1.1-2.21)0.0111.87 (1.26-2.77)0.0016
 Other adjuvant800.49 (0.2-1.18)0.112.84 (1.09-7.41)0.0250.29 (0.07-1.25)0.076
HER2 status
 Positive4240.75 (0.56-1.01)0.0531.41 (1.06-1.88)0.0160.75 (0.57-1)0.05
 Negative6410.64 (0.51-0.81)0.000121.59 (1.25-2.01)0.000110.62 (0.49-0.78)