Stem Cells International / 2023 / Article / Tab 2 / Research Article
[Retracted] Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer Table 2 Evaluation of the association between PTTG expression and clinical prognosis in gastric cancer using the Kaplan-Meier plotting method and other clinicopathological variables.
Clinicopathological characteristics PTTG1 PTTG2 PTTG3P Overall survival ( ) Hazard ratio valueHazard ratio valueHazard ratio valueSex Female 244 0.44 (0.29-0.65) 1.64 (1.16-2.33) 0.0049 0.56 (0.39-0.81) 0.0019 Male 566 0.79 (0.64-0.98) 0.032 1.43 (1.15-1.77) 0.001 0.67 (0.53-0.85) Stage 1 69 0.22 (0.05-0.97) 0.028 3.5 (0.99-12.34) 0.038 0.34 (0.12-0.92) 0.027 2 145 0.53 (0.28-0.98) 0.039 1.6 (0.89-2.9) 0.12 0.43 (0.23-0.78) 0.0044 3 319 0.6 (0.45-0.8) 0.00051 1.4 (1.04-1.86) 0.023 0.68 (0.51-0.9) 0.0075 4 152 0.54 (0.35-0.82) 0.0034 0.75 (0.51-1.11) 0.15 0.64 (0.42-0.98) 0.037 Stage T 2 253 0.61 (0.4-0.93) 0.021 1.43 (0.86-2.39) 0.16 0.52 (0.34-0.8) 0.0022 3 208 0.69 (0.47-0.99) 0.044 1.15 (0.82-1.62) 0.42 0.68 (0.49-0.96) 0.029 4 39 0.44 (1.09-1.03) 0.054 0.7 (0.28-1.79) 0.46 0.63 (0.27-1.49) 0.29 Stage N 0 76 0.25 (0.07-0.84) 0.015 3.87 (1.65-9.08) 0.00083 0.46 (0.2-1.08) 0.068 1 232 0.5 (0.33-0.75) 0.00072 1.45 (0.96-2.18) 0.076 0.46 (0.31-0.7) 0.00021 2 129 0.59 (0.37-0.93) 0.021 0.54 (0.33-0.87) 0.11 1.46 (0.85-2.58) 0.16 3 76 0.49 (0.29-0.85) 0.0094 0.58 (0.32-1.06) 0.071 0.48 (0.27-0.87) 0.013 437 0.58 (0.45-0.76) 1.14 (0.88-1.48) 0.33 0.55 (0.42-0.73) Stage M 0 459 0.55 (0.41-0.73) 1.31 (1-1.73) 0.053 0.53 (0.4-0.7) 1 58 0.53 (0.29-0.98) 0.039 0.7 (0.37-1.32) 0.26 0.52 (0.27-1) 0.045 Lauren classification Intestinal 336 0.55 (0.4-0.76) 0.00024 1.61 (1.17-2.22) 0.0031 0.5 (0.36-0.68) Diffuse 248 0.63 (0.44-0.9) 0.01 1.33 (0.95-1.88) 0.098 0.6 (0.4-0.89) 0.01 Differentiation Poor 166 1.75 (1.17-2.63) 0.0057 1.28 (0.85-1.92) 0.23 1.2 (0.8-1.81) 0.37 Moderate 67 0.63 (0.31-1.25) 0.18 0.63 (0.33-1.2) 0.15 0.51 (0.26-0.99) 0.042 High 32 0.57 (0.23-1.43) 0.23 1.55 (0.65-3.69) 0.32 0.31 (0.12-0.8) 0.011 Treatment Surgery alone 393 0.6 (0.44-0.81) 1.2 (0.9-1.6) 0.21 0.61 (0.46-0.82) 0.00072 5 FU-based adjuvant 157 2.12 (1.4-3.21) 0.00032 1.56 (1.1-2.21) 0.011 1.87 (1.26-2.77) 0.0016 Other adjuvant 80 0.49 (0.2-1.18) 0.11 2.84 (1.09-7.41) 0.025 0.29 (0.07-1.25) 0.076 HER2 status Positive 424 0.75 (0.56-1.01) 0.053 1.41 (1.06-1.88) 0.016 0.75 (0.57-1) 0.05 Negative 641 0.64 (0.51-0.81) 0.00012 1.59 (1.25-2.01) 0.00011 0.62 (0.49-0.78)