Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs)

<div>Effects of ginsenoside Rg1 on the PI3K/AKT signaling pathway and expressions of cyclins and CDKs in hAD-MSCs. (a, b) The expressions of Akt, phospho-Akt, cyclin D1, cyclin E1, CDK2, and CDK4 in hAD-MSCs were analyzed (a) and compared (b) by western blot after pretreatment of hAD-MSCs with or without LY294002 for 1 h followed by the treatment with or without Rg1 in the control, Rg1, Rg1+LY294002, and LY294002 groups. <svg height="10.7395pt" id="M29" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 50.9184 10.7395" width="50.9184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 262C225 236 198 227 145 220C133 201 125 177 126 158C141 148 167 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Stem Cells International

fig3

Figure 3

Figure 3: Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs) 