Review Article
Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review
Table 3
The main role of the growth factors.
| Growth factor | Main mechanism |
| TGF-β | Osteogenic and chondrogenic differentiation | BMPs | Chondrogenic, osteogenic, and osteoinductive | bFGF | Angiogenesis, proliferation, and osteogenic differentiation | NGF | Promoting bone metabolism and osteogenic differentiation | PDGF | Osteogenic and endothelial differentiation with gene expression | IGF | Anabolic and catabolic effects on osteogenesis | VEGF | Osteoinductive, chemotactic, and angiogenesis | FGF | Angiogenesis, proliferation, and osteogenic differentiation |
|
|
TGF-β, transforming growth factor-β; BMPs, bone morphogenetic proteins; BFGF, basic fibroblast growth factor; NGF, nerve growth factor; PDGF, platelet-derived growth factor; IGF, insulin-like growth factor; VEGF, vascular endothelial growth factor; FGF, fibroblast growth factor.
|