Review Article

Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review

Table 4

Application of DPSCs and SHED for BTE in different animal models and scaffolds.

AuthorAnimal modelStem cellsScaffoldMode of transplantation

Miura et al. [15]Immunocompromised miceSHEDsHA/TCPSubcutaneous implantation
Li et al. [126]MRL/Ipr miceSHEDsHA/TCPIntravenous administration
Beztsinna et al. [107]Immunocompromised miceDPSCs3D Bioglass®Intraperitoneal implantation
Keller et al. [105]RatsDPSCsHA/TCPCranial defect
Jang et al. [102]RatsSHEDsCollagen matrixMaxillary alveolar bone defect
Ghavimi et al. [128]RatsDPSCsWoven bone (WB)Mandibular bone defect
Du et al. [129]Immunodeficient miceSHEDs/hDPSCs/hBMSCsPolylactic-coglycolic acid barrier membraneCalvaria defect
Hu et al. [134]DogsSHEDsCell-free collagen scaffoldMandibular bone defect
Chen et al. [135]SheepDPSCsNoneFemoral defects
Chan et al. [136]SheepDPSCsBonelike®Femoral defects
Zheng et al. [108]PigsDPSCsHA/TCPPeriodontal bone defect
Wu et al. [111]PigsDPSCsCSD, α-CSH/ACP, and β-TCP scaffoldMandibular bone defect