Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review

Table 4

Application of DPSCs and SHED for BTE in different animal models and scaffolds.

Author	Animal model	Stem cells	Scaffold	Mode of transplantation
Miura et al. [15]	Immunocompromised mice	SHEDs	HA/TCP	Subcutaneous implantation
Li et al. [126]	MRL/Ipr mice	SHEDs	HA/TCP	Intravenous administration
Beztsinna et al. [107]	Immunocompromised mice	DPSCs	3D Bioglass®	Intraperitoneal implantation
Keller et al. [105]	Rats	DPSCs	HA/TCP	Cranial defect
Jang et al. [102]	Rats	SHEDs	Collagen matrix	Maxillary alveolar bone defect
Ghavimi et al. [128]	Rats	DPSCs	Woven bone (WB)	Mandibular bone defect
Du et al. [129]	Immunodeficient mice	SHEDs/hDPSCs/hBMSCs	Polylactic-coglycolic acid barrier membrane	Calvaria defect
Hu et al. [134]	Dogs	SHEDs	Cell-free collagen scaffold	Mandibular bone defect
Chen et al. [135]	Sheep	DPSCs	None	Femoral defects
Chan et al. [136]	Sheep	DPSCs	Bonelike®	Femoral defects
Zheng et al. [108]	Pigs	DPSCs	HA/TCP	Periodontal bone defect
Wu et al. [111]	Pigs	DPSCs	CSD, α-CSH/ACP, and β-TCP scaffold	Mandibular bone defect