EVL Promotes Osteo-/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway

<div>Involvement of the MAPK signaling pathway in EVL-mediated osteo-/odontogenic differentiation of hDPSCs. (a) Western blot analyses of p38 MAPK, p-p38 MAPK, ERK, p-ERK, JNK, and p-JNK expressions were measured in hDPSCs transfected with si-EVL and si-NC. (b) Protein expression levels of p38 MAPK, p-p38 MAPK, ERK, p-ERK, JNK, and p-JNK in hDPSCs transfected with pMV and pM-EVL. (c) The p-JNK/JNK ratio was measured in hDPSCs transfected with pMV and pM-EVL. (d) The p-JNK/JNK ratio was measured in hDPSCs transfected with si-EVL and si-NC. (e) The p-p38/p38 ratio was measured in hDPSCs transfected with pM-EVL and pMV. 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Stem Cells International

fig4

Figure 4

Figure 4: EVL Promotes Osteo-/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway 