Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neuroinflammation, and Apoptosis

<div>The representative cresyl violet-stained sections of the Cornu Ammonis (CA1, CA2, and CA3), and dentate gyrus (DG) regions in rat hippocampus of different groups. Darkened and contracted cells (black arrows), areas of cell loss (red arrows), and pyknotic nuclei (arrowheads). Con: control; Dia: diabetes; Dia + CM: WJMSC-CM-treated diabetic group; Dia + INS: insulin-treated diabetic group; Dia + DMEM: DMEM-treated diabetic group.</div>

Stem Cells International

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Figure 8

Figure 8: Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neuroinflammation, and Apoptosis 

Figure 8 | Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neuroinflammation, and Apoptosis 