Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Trophoblast Cell Proliferation and Migration by Targeting TFPI2 in Preeclampsia
Table 1
Clinical characteristics of preeclampsia and normal pregnancies.
Normal n = 40
PE n = 34
P value
Maternal age (years)
26.4 ± 3.7
27.6 ± 3.9
0.164
Body mass index (kg/m2)
25.1 ± 4.4
25.7 ± 5.1
0.085
Time of pregnancy before delivery (week)
39.1 ± 0.7
32.9 ± 1.6
0.021
Systolic blood pressure (mm Hg)
112.3 ± 3.5
163.1 ± 9.2
0.005
Diastolic blood pressure (mm Hg)
71.7 ± 3.1
108.2 ± 9.3
0.002
Proteinuria (g/d)
0.15 ± 0.06
1.39 ± 0.71
<0.001
Blood urea nitrogen (U/L)
3.76 ± 1.13
4.02 ± 1.25
0.132
Blood platelet (×109)
176.22 ± 60.31
170.36 ± 64.09
0.213
Body weight of infant (g)
3316 ± 215
2208 ± 623
0.012
Note. The data presented are mean ± SD. The comparison of data between the two groups was done by unpaired Student’s t-test.