Chromosomal Instability in Various Generations of Human Mesenchymal Stem Cells Following the Therapeutic Radiation

Figure 1

Isolation and extraction steps of MSCs: (a) the Wharton’s jelly was carefully separated and cut into small pieces and it was washed several times; (b) extracted cells, as well as Wharton’s jelly pieces, were seeded in a culture medium. Wharton’s jelly pieces were removed from the flask after 18–21 days; (c) extracted MSCs appeared as spindle-shaped and fibroblast-like cells that adhere to the substrate; (d) osteogenic differentiation of hUCMSc; (e) adipogenic differentiation of MSCs.

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