Review Article

Prognostic Value of MTV and TLG of 18F-FDG PET in Patients with Stage I and II Non-Small-Cell Lung Cancer: a Meta-Analysis

Table 1

Features of included studies.

StudyYearCountryStudy periodFollow-up duration (months)Median age (range), yearsNo. of patientsTNM stagingEnd pointsStudy designHistologyTreatment

Suman et al.2020Japan2010.6–2016.1044.873 (53–85)39IOS PFSRetroAdenocarcinoma
Squamous cell carcinoma
Radiotherapy
Domachevsky et al.2015Israel2007–20126068.7 ± 8.9181I-IIOSRetroAdenocarcinoma
Squamous cell carcinoma
Mixed/sarcomatoid
Bronchioloalveolar
Adenocarcinoma with bronchioloalveolar
Surgery
Seong et al.2015Korea2006.2–2011.1236.663.03 ± 10.01248IOSRetroAdenocarcinoma
Nonadenocarcinoma
Surgery
Seung et al.2013Korea2003.7–2006.126063 (23–83)529I-IIOS DFSRetroAdenocarcinoma
Squamous cell carcinoma
Large cell carcinoma
Adenosquamous carcinoma
Others
Surgery
Chemotherapy
Radiotherapy
Charles et al.2013USA2007.5–2012.1225.173.350IOS RFSRetroAdenocarcinoma
Squamous cell carcinoma
Others
Radiotherapy
Melloni et al.2013Italy2005.1–2011.121 (3–68)68(40–85)99IPFSRetroAdenocarcinoma
Others
Surgery
Abelson et al.2012USA2005.9–2009.1213.280.1(57.6–93.4)84IOSRetroSquamous cell carcinoma
Adenocarcinoma
Non-small-cell
Atypia
Radiotherapy
Lin Y et al.2012Taiwan2009.1–2011.224(8–36)63(38–85)62IPFSRetroSquamous cell carcinoma
Adenocarcinoma
Surgery

Abbreviations: Retro = retrospective; PFS = progression-free survival; DFS = disease-free survival; RFS = recurrence-free survival; OS = overall survival.