Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System

Table 1

Effects of Ex-4 on serum levels of ALT, AST, urea, and creatinine in sham- and burn-injured mice.

Groups	Treatment	ALT (U/L)	AST (U/L)	Ratio (AST/ALT)	Urea (mmol/L)	Creatinine (μmol/L)	Ratio (urea/creatinine)
Sham	PBS
	Ex-4
	Ex-4+Prop					^#
	Prop					^&
Burn	PBS
	Ex-4
	Ex-4+Prop	^#	^#	^#	^#	^#	^#
	Prop		^&		^&

Animals were pretreated with normal saline or Prop 30 min prior to injury and then were injected with Ex-4 (2.4 nmol/kg) 30 min after injury. Serum was collected 24 h postburn and the biochemistry parameters were detected. Data are presented as mean ± SD. mice/group. vs. PBS, vs. Ex-4, and vs. Ex-4+Prop. The values of Prop group were not compared with Ex-4 group. Student’s -test.